How much does it cost to drive from Chicago to St. Louis?

Driving fuel + tolls cost is calculated live based on today's gas prices in MO and your vehicle's MPG.

How far is Chicago from St. Louis?

Approximate driving distance and time are computed from real highway routing.

Cost to drive

Chicago to St. Louisin a 2025 Toyota Camry

Live fuel-cost estimate from Chicago, IL to St. Louis, MO driving a 2025 Toyota Camry, using today's average pump prices in MO, real highway distance, tolls, and recommended refuel stops along the route.

Total cost

$40.27

Distance

328 mi

Drive time

5h 28m

Fuel

10.2 gal

Gas: $3.45/gal

Cost breakdown

Fuel (10.2 gal @ $3.45/gal route avg)$35.35

Tolls (estimated)$4.92

Cost per mile$0.123

Refuel stops0

Range per fill506 mi

Vehicle

Make / ModelToyota Camry

Year2025

Fuel typegas

MPG (combined)32

Tank (gal)15.8

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FAQ

Driving from Chicago, IL to St. Louis, MO costs about $40.27 one way in fuel and tolls for a Toyota Camry at today's gas prices.