Mercedes-Benz · gas
Mercedes-Benz S-Class fuel economy & road trip cost
The Mercedes-Benz S-Class (2015–2025) is rated at 23 combined MPG with a 21.1 gallon tank, giving roughly 388 miles between stops once you keep a sensible reserve.
Combined MPG
23
Tank
21.1 gal
Usable range
388 mi
Cost per mile
$0.150
Gas cost per 100 miles in a Mercedes-Benz S-Class
| Pump price ($/gal) | 100 miles | 300 miles | Full tank |
|---|---|---|---|
| $3.00 | $13.04 | $39.13 | $63.30 |
| $3.50 | $15.22 | $45.65 | $73.85 |
| $4.00 | $17.39 | $52.17 | $84.40 |
| $4.50 | $19.57 | $58.70 | $94.95 |
| $5.00 | $21.74 | $65.22 | $105.50 |
Highway-heavy trips usually beat the combined rating; city traffic and roof loads reduce it.
Popular trips in a Mercedes-Benz S-Class
- Las Vegas to Phoenix · ~$45
- Las Vegas to Los Angeles · ~$41
- Los Angeles to San Francisco · ~$62
- Los Angeles to San Diego · ~$20
- Los Angeles to Las Vegas · ~$41
- San Francisco to Los Angeles · ~$62
- New York to Boston · ~$34
- New York to Washington · ~$36
- New York to Philadelphia · ~$14
- Chicago to Indianapolis · ~$29
- Chicago to Detroit · ~$42
- Chicago to St. Louis · ~$47
Fuel figures on this page are modelled estimates built from published EPA combined MPG ratings and curated regional pump-price baselines. They are not live station quotes — always confirm the price at the pump before you travel.