Toyota · hybrid
Toyota Sienna fuel economy & road trip cost
The Toyota Sienna (2021–2025) is rated at 36 combined MPG with a 18 gallon tank, giving roughly 518 miles between stops once you keep a sensible reserve.
Combined MPG
36
Tank
18 gal
Usable range
518 mi
Cost per mile
$0.096
Gas cost per 100 miles in a Toyota Sienna
| Pump price ($/gal) | 100 miles | 300 miles | Full tank |
|---|---|---|---|
| $3.00 | $8.33 | $25.00 | $54.00 |
| $3.50 | $9.72 | $29.17 | $63.00 |
| $4.00 | $11.11 | $33.33 | $72.00 |
| $4.50 | $12.50 | $37.50 | $81.00 |
| $5.00 | $13.89 | $41.67 | $90.00 |
Highway-heavy trips usually beat the combined rating; city traffic and roof loads reduce it.
Popular trips in a Toyota Sienna
- Las Vegas to Phoenix · ~$29
- Las Vegas to Los Angeles · ~$26
- Los Angeles to San Francisco · ~$39
- Los Angeles to San Diego · ~$13
- Los Angeles to Las Vegas · ~$26
- San Francisco to Los Angeles · ~$39
- New York to Boston · ~$21
- New York to Washington · ~$23
- New York to Philadelphia · ~$9
- Chicago to Indianapolis · ~$19
- Chicago to Detroit · ~$27
- Chicago to St. Louis · ~$30
Fuel figures on this page are modelled estimates built from published EPA combined MPG ratings and curated regional pump-price baselines. They are not live station quotes — always confirm the price at the pump before you travel.